Preferential reduction of quadriceps over respiratory muscle strength and bulk after lung transplantation for cystic fibrosis

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Preferential reduction of quadriceps over respiratory muscle strength and bulk after lung transplantation for cystic fibrosis.

BACKGROUND In the absence of complications, recipients of lung transplants for cystic fibrosis have normal pulmonary function but the impact of the procedure on the strength and bulk of respiratory and limb muscles has not been studied. METHODS Twelve stable patients who had undergone lung transplantation for cystic fibrosis 48 months earlier (range 8-95) and 12 normal subjects matched for ag...

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CYSTIC FIBROSIS Preferential reduction of quadriceps over respiratory muscle strength and bulk after lung transplantation for cystic fibrosis

Background: In the absence of complications, recipients of lung transplants for cystic fibrosis have normal pulmonary function but the impact of the procedure on the strength and bulk of respiratory and limb muscles has not been studied. Methods: Twelve stable patients who had undergone lung transplantation for cystic fibrosis 48 months earlier (range 8–95) and 12 normal subjects matched for ag...

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Lung transplantation in cystic fibrosis.

Lung transplantation has become a viable option for those cystic fibrosis (CF) patients with end-stage lung disease. Despite the challenges that the CF patients present, the survival seen after lung transplantation is more favorable than seen in patients with chronic obstructive pulmonary disease and pulmonary fibrosis. Although the CF patients with severe respiratory disease usually are infect...

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Effect of systemic inflammation on inspiratory and limb muscle strength and bulk in cystic fibrosis.

RATIONALE Diaphragm thickness is increased in cystic fibrosis (CF), but it shows a marked variability between patients. The variable response of the diaphragm to loading may reflect the combined and opposite effects of training by the respiratory disease and systemic inflammation. OBJECTIVES To assess the impact of systemic inflammation on diaphragm and limb muscle strength and bulk in adult ...

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GI complications after lung transplantation in patients with cystic fibrosis.

STUDY OBJECTIVE Lung transplantation is now available for patients with cystic fibrosis (CF) and end-stage lung disease. While pulmonary graft function is often considered the major priority following transplantation, the nonpulmonary complications of this systemic disease also continue. We examined the GI complications in a cohort of patients who underwent transplantation. DESIGN This was a ...

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ژورنال

عنوان ژورنال: Thorax

سال: 2004

ISSN: 0040-6376

DOI: 10.1136/thx.2004.021766